10 Cities Visited by Paul on His Missionary Journeys

Have you ever wondered which ancient cities the apostle Paul traveled to during his missionary journeys? These cities played a crucial role in the spread of early Christianity and shaped the foundations of the faith we know today.

As we delve into each city, you’ll uncover fascinating stories of faith, miracles, persecution, and the birth of churches. From Paul’s home base in Antioch in Syria to the riotous city of Ephesus and the influential center of Jerusalem, each destination holds its unique significance in Paul’s missionary endeavors.

Come with us as we unravel the hidden tales behind the cities visited by Paul and gain a deeper understanding of the early Christian movement.

Antioch in Syria

In Paul’s missionary journeys, Antioch in Syria served as his home base and the pivotal starting point. This ancient city held significant importance in the development of early Christianity.

Located in modern-day Turkey, Antioch was a bustling cosmopolitan center, known for its diverse population and cultural richness. It played a crucial role in spreading the message of Jesus Christ to the Gentiles.

It was in Antioch that the followers of Jesus were first called Christians (Acts 11:26). This term became synonymous with the believers who embraced the teachings of Jesus and sought to follow in his footsteps.

“The disciples were called Christians first in Antioch.”

As Paul’s home base, Antioch provided a launchpad for his missionary endeavors. From here, he embarked on his transformative journeys, traversing vast distances to share the gospel, establish churches, and strengthen the faith of believers.

The city of Antioch itself was no stranger to diversity and multiculturalism, making it an ideal starting point for Paul’s mission. It presented a unique opportunity for him to engage with people from various backgrounds, cultures, and belief systems.

Paul’s time in Antioch, both as his home base and the place of the first mention of Christians, laid the foundation for the spread of Christianity throughout the Roman Empire. The city remains an important landmark in Christian history, symbolizing the transformative power of the message of Jesus Christ.

Key PointsDetails
LocationSituated in modern-day Turkey
SignificancePaul’s home base and starting point for his missionary journeys
Origin of the term “Christians”Followers of Jesus were first called Christians in Antioch (Acts 11:26)
DiversityA cosmopolitan city with a diverse population
Missionary endeavorsLaunchpad for Paul’s journeys to spread the gospel and establish churches

Antioch in Syria will always hold a special place in the story of Christianity, serving as the birthplace of the term “Christians” and the springboard for Paul’s impactful missionary journeys that shaped the course of early Christianity.


Shortly after his conversion on the road to Damascus, Paul spent time in this city preaching the gospel (Acts 9:19-20). It was a transformative moment for Paul, as he went from persecuting Christians to becoming an ardent follower of Jesus.

Paul’s conversion on the road to Damascus is a well-known event in Christian history. As he journeyed to Damascus with the intention of persecuting more followers of Jesus, he encountered a blinding light and heard the voice of Jesus speaking to him. This experience led to his immediate conversion and changed the course of his life forever.

Paul wasted no time in sharing the good news of Jesus Christ in Damascus. He began preaching the gospel, causing quite a stir among the people. His powerful message and unwavering faith inspired many to believe in Jesus and join the growing community of followers.

“And immediately he [Paul] proclaimed Jesus in the synagogues, saying, ‘He is the Son of God.’ And all who heard him were amazed and said, ‘Is not this the man who made havoc in Jerusalem of those who called upon this name? And has he not come here for this purpose, to bring them bound before the chief priests?’ But Saul [Paul] increased all the more in strength, and confounded the Jews who lived in Damascus by proving that Jesus was the Christ.”

Acts 9:20-22 ESV

Damascus was an important city in Paul’s missionary journeys. It served as a significant hub for spreading the gospel message to both Jews and Gentiles. The impact of Paul’s preaching in Damascus cannot be overstated, as it laid the foundation for the growth of Christianity in the region.



In the city of Lystra, an extraordinary event took place during Paul’s missionary journey. He encountered a man who had been lame from birth and, through the power of healing bestowed upon him by God, Paul made the man whole again (Acts 14:8-10). This miraculous healing led to a misunderstanding among the locals, who mistook Paul and his companion, Barnabas, as gods in human form (Acts 14:11-13).

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However, Paul quickly corrected the misconception and emphasized that he and Barnabas were mere mortal messengers of the one true God (Acts 14:14-15). Despite the initial confusion, Paul’s healing in Lystra served as a testament to his divine calling and the power of God’s grace.

Lystra was not only a place of healing but also the hometown of Timothy, a faithful disciple and close companion of Paul. Timothy became a trusted partner in Paul’s missionary endeavors, sharing in the mission to spread the gospel message to all nations (Acts 16:1-3). Together, they experienced countless challenges and triumphs throughout their shared ministry.

Let’s delve deeper into the significant role that Lystra played in Paul’s journey and the impact it had on the early spread of Christianity.

Key Events in Lystra

Miraculous HealingPaul heals a man lame from birth, leading to a misunderstanding that he and Barnabas are gods (Acts 14:8-20)
Timothy’s OriginLystra is the hometown of Timothy, who becomes a trusted companion of Paul (Acts 16:1)


Derbe was a significant city visited by Paul and Barnabas during their first missionary journey. In Derbe, they had the opportunity to preach the gospel and share the teachings of Jesus Christ with the local residents. Their efforts were not in vain, as many people in Derbe accepted their message and became disciples of Christ.

Derbe played a crucial role in Paul’s mission to spread the gospel and establish Christian communities. The impact of Paul and Barnabas’ preaching in Derbe is evidence of the transformative power of their message and the receptiveness of the people.


Their time in Derbe highlights the dedication and perseverance of Paul and Barnabas in their mission to bring the good news to various cities. Despite encountering challenges and opposition in other places, the reception in Derbe was a testament to the effectiveness of their preaching and the willingness of the people to embrace the gospel.

Through their work in Derbe and other cities, Paul and Barnabas laid the foundation for the growth of Christianity and the establishment of local churches. The impact of their ministry continues to inspire believers today, reminding us of the transformative power of the gospel and the importance of sharing it with others.


Philippi holds significant historical and religious importance as the first city in Europe where Paul established a church. Located in present-day Greece, Philippi became a pivotal location in Paul’s missionary journeys.

“And from there (Troas) to Philippi, which is a leading city of the district of Macedonia and a Roman colony. We remained in this city some days.” – Acts 16:12

During his stay in Philippi, Paul and his companion Silas encountered a young slave girl possessed by a spirit of divination. Paul commanded the spirit to leave her, which led to their arrest and subsequent imprisonment (Acts 16:16-24). Their imprisonment serves as a testament to the challenges they faced while spreading the gospel.

However, the story takes a miraculous turn. While Paul and Silas were praying and singing hymns to God in their jail cell, a violent earthquake shook the foundations of the prison. The doors were opened, and everyone’s bonds were unfastened. This supernatural event allowed Paul and Silas to escape, demonstrating the power of God’s intervention (Acts 16:25-26).


The story of Philippi showcases both the hardships and the freedom experienced by Paul and his companions. From the establishment of the first church in Europe to their imprisonment and subsequent deliverance, Philippi holds a special place in the narrative of early Christianity.

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In Athens, Paul had a profound impact as he delivered his famous sermon at the Areopagus. This significant event took place during his missionary journeys, where Paul addressed the Athenians and introduced them to the God of Christianity. The sermon was a response to the Athenians’ altar dedicated to an unknown god, and Paul took the opportunity to share the message of Jesus Christ (Acts 17:16-34).

“…what you worship as something unknown I am going to proclaim to you. The God who made the world and everything in it is the Lord of heaven and earth and does not live in temples built by human hands…”

– Acts 17:23-24 (NIV)

Paul’s visit to Athens allowed him to engage with the intellectual and philosophical center of the ancient world, challenging their beliefs and inviting them to embrace the truth of Christianity. This encounter serves as a powerful example of Paul’s willingness to meet people where they were and share the message of salvation.

The Impact of Paul’s Sermon

Paul’s sermon at the Areopagus marked a significant moment in the spread and acceptance of Christianity. While some mocked his message, others were intrigued and wanted to hear more (Acts 17:32). Though the immediate response varied, the sermon planted seeds of curiosity and belief, contributing to the growth of the early Church in Athens.

Introducing Christianity to Athens

Athens was renowned for its cultural, philosophical, and religious significance. By addressing the Athenians in their own philosophical context, Paul demonstrated the compatibility of Christianity with their intellectual pursuits. His sermon challenged the prevalent worship of idols and false gods while offering the hope of a personal relationship with the one true God.

Through his visit to Athens and the sermon at the Areopagus, Paul left an indelible mark on the city and introduced a new way of thinking and worship. His willingness to engage with different cultures and adapt his approach to their unique contexts showcases the universality and adaptability of the Christian message.

Athens sermon at the Areopagus

As we continue to explore Paul’s missionary journeys, let’s now turn our attention to another significant city: Corinth. Join us as we delve into the impact of Paul’s time in Corinth and the establishment of a vibrant Christian community.


Corinth played a significant role in Paul’s missionary journeys. He spent 18 months here, during which he wrote several of his epistles that form a crucial part of the New Testament. In addition to writing, Paul also dedicated his time and energy to establishing a church in Corinth.

Located in Greece, Corinth was a bustling city known for its commerce, diversity, and cultural significance. It was strategically positioned as a major trade hub, attracting people from various backgrounds and cultures. This diverse population presented both opportunities and challenges for Paul’s mission.

Paul’s extended stay in Corinth allowed him to build strong relationships within the community and deeply engage with the Corinthians. He preached the gospel, taught, and mentored the believers, nurturing a thriving church in the city.

“I thank my God always concerning you for the grace of God which was given you in Christ Jesus.”

1 Corinthians 1:4

Paul’s epistles to the Corinthians address a wide range of issues and guidance for living a life that honors God. These letters provide insights into the challenges faced by the church, addressing topics such as unity, spiritual gifts, ethical matters, and the resurrection.

As we explore Corinth, it is important to note that the city was not without its struggles. The Corinthians faced conflicts, moral dilemmas, and divisions within the church. Paul’s epistles serve as a guide for navigating these challenges, offering wisdom and encouragement.



During his missionary journeys, Paul spent approximately three years in Ephesus, which was the longest period he stayed in one place. His time in Ephesus had a significant impact on both the local community and the spread of Christianity.

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Paul’s preaching in Ephesus stirred up controversy and led to a riot among the silversmiths who crafted shrines for the goddess Artemis (Acts 19). The silversmiths, fearing a decline in their business due to the growing number of converts to Christianity, incited a mob against Paul and his followers.

“Great is Artemis of the Ephesians!”

In the midst of the chaos, the city clerk managed to calm the crowd and assure them that there was a legal process to address any grievance (Acts 19:35-41). However, this incident demonstrates the impact of Paul’s preaching and the disruption it caused to the established religious practices in Ephesus.

Despite the challenges he faced, Paul’s time in Ephesus left a lasting impression. The influence of his teachings and the establishment of a strong Christian community in the city continued long after his departure.

The Temple of Artemis: One of the Seven Wonders of the Ancient World

Ephesus was renowned for its Temple of Artemis, which was considered one of the Seven Wonders of the Ancient World. This magnificent temple served as a focal point for the worship of Artemis, the Greek goddess of hunting and fertility.


The Temple of Artemis was a symbol of religious and cultural significance in Ephesus. Its grandeur and architectural marvel attracted visitors from far and wide. The presence of this iconic temple in the city further heightened the conflict between the followers of Artemis and those embracing the teachings of Paul.

CityDuration of StaySignificant Events
EphesusApproximately three yearsRiot among the silversmiths, preaching causing controversy


After leaving Philippi, Paul and Silas arrived in Thessalonica, where they founded a church in the name of Jesus Christ. Thessalonica, a bustling city located in present-day Greece, was an important center in Macedonia during Paul’s time. The establishment of a church in Thessalonica demonstrated the rapid spread of Christian faith and the impact of Paul’s missionary efforts.

However, the founding of the church in Thessalonica was not without its challenges. This vibrant city was a melting pot of diverse cultures, religions, and ideologies, which created an atmosphere of opposition towards the message of Christianity. Paul and his companions faced resistance and hostility from those who rejected their teachings.

In the biblical account, we read that some of the Jews in Thessalonica were envious of the growing number of Gentile converts and sought to discredit Paul and the other missionaries. They stirred up a mob, causing unrest and endangering the safety of the newly formed church. Faced with this opposition, Paul and Silas made the difficult decision to leave Thessalonica and continue their journey to spread the gospel elsewhere.

Despite the challenges and opposition encountered in Thessalonica, the church that Paul founded continued to thrive and become a beacon of hope for believers in the region. The epistles of 1 Thessalonians and 2 Thessalonians in the New Testament were written by Paul to the church in Thessalonica, offering guidance, encouragement, and instruction.

Opposition from some Jews and GentilesPaul and Silas decided to leave Thessalonica to protect the safety of the believers and to continue their mission in other cities.
Threats to the stability of the newly formed churchPaul wrote the epistles of 1 Thessalonians and 2 Thessalonians, providing guidance and encouragement to the believers and addressing their concerns.
Growth and perseverance of the church despite oppositionThe church in Thessalonica continued to thrive, becoming a strong community of believers who remained faithful to the teachings of Paul and the gospel message of Jesus Christ.

Despite the challenges faced by Paul and his companions in Thessalonica, the impact of their ministry was undeniable. The establishment of a church in this vibrant city became a cornerstone in the spread of Christianity in the region, leaving a lasting legacy that continues to inspire believers today.

What is the significance of the cities visited by Paul on his missionary journeys in relation to the cities known for their wickedness in the Bible?

The cities visited by Paul on his missionary journeys are significant in relation to the cities known for their biblical wickedness. These cities with biblical wickedness were important locations for spreading the message of Christianity and serving as examples of redemption and transformation. Paul’s efforts in these cities highlighted the power of faith and the potential for change.


Paul’s final visit to Jerusalem marked a significant turning point in his life. Although it wasn’t a traditional missionary journey, it had a profound impact on the course of his ministry.

During his time in Jerusalem, Paul encountered a series of events that would ultimately lead to his arrest. These events set in motion a chain of events that would result in his journey to Rome as a prisoner. It is in Jerusalem that Paul’s faith and resolve were tested to their limits.

Jerusalem holds great historical and spiritual significance, being the city where Jesus was crucified and resurrected. For Paul, it was the heart of religious authority and the center of the early Christian movement. His final visit to this sacred city demonstrated his unwavering commitment to fulfilling his mission, even in the face of impending danger and uncertainty.